Oscar Isaac appeared on Jimmy Fallon’s show last night, bringing an exclusive new Oscar Isaac Frankenstein clip from Guillermo del Toro’s much-anticipated Netflix film adaptation. The glimpse showcases Victor Frankenstein’s initial attempt at reanimating dead tissue before a group of doubtful colleagues. This pivotal scene highlights the eerie proto-creature made up of a head, torso, and one arm, which briefly interacts by catching and dropping a ball, sparking intrigue among those watching.
The Emotional Themes Behind Frankenstein Explored by Oscar Isaac
In a recent interview with Backstage.com, Oscar Isaac delved into the deeper emotional fabric driving the story. He revealed how discussions with director Guillermo del Toro focused heavily on the influence of fathers and the inheritance of pain. Isaac explained how their conversations connected emotionally to the film’s themes, framing everything as an exploration of one’s reaction to the environment into which they are born.
“Early on, we talked so much about our fathers, and the way that pain gets passed down,”
Isaac shared.
[The conversation] was always emotionally connected to everything being a reaction and an investigation of the world that one is born into.”
Oscar Isaac, actor
The actor also described their shared artistic vision to challenge accepted realities, including nature, death, and the legacy left by previous generations. This defiance of death and fear became a central motif in their creative process.
“[Del Toro and I] talked a lot about wanting to defy our fathers, and nature, and the future, and death. The defiance of death is a big one,”
he said.
“The ‘[frick] it’ attitude, the willingness to destroy because one can’t sit in the pain or the fear of being seen, of actually being seen. You’d rather self-immolate.”
Oscar Isaac, actor
Visual Material Highlights Cast and Characters Ahead of Premiere
The Oscar Isaac Frankenstein clip was accompanied by several recently released character posters that spotlight key actors involved in the production. The film is led by Oscar Isaac as Victor Frankenstein, with Jacob Elordi portraying the Creature and Mia Goth as Elizabeth Harlander. Other notable cast members include Felix Kammerer as William Frankenstein and Christoph Waltz as Heinrich Harlander.
“Oscar Isaac. Victor Frankenstein. FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7.”
Netflix, official tweet
“Jacob Elordi. The Creature. FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7.”
Netflix, official tweet
“Mia Goth. Elizabeth Harlander. FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7.”
Netflix, official tweet
“Felix Kammerer. William Frankenstein. FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7.”
Netflix, official tweet
“Christoph Waltz. Heinrich Harlander. FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7.”
Netflix, official tweet
Accompanying the visual promotions, artist James Jean posted an uncropped version of his official poster design for the film, further generating excitement in the lead-up to release.
“Good Morning! Here is the full, uncropped poster I did for @RealGDT @FrankensteinGDT”
James Jean, artist
Plot Overview and Del Toro’s Personal Connection to Frankenstein
The narrative revolves around Victor Frankenstein, a brilliant yet egotistical scientist played by Oscar Isaac, who embarks on a groundbreaking experiment to bring a creature to life. This venture, however, leads to tragic consequences both for the creator and his creation, exploring themes of ambition, mortality, and identity.
Director Guillermo del Toro expressed the deeply personal nature of this film project, describing it as the culmination of a lifelong fascination sparked by viewing James Whale’s Frankenstein films at a young age. He likened the Gothic horror genre to a sanctuary of meaning, comparing the iconic actor Boris Karloff to a figure of reverence in his own creative journey.
“This film concludes a quest that started at age 7, when I saw James Whale’s Frankenstein films for the first time. I felt the jolt of recognition in that seminal moment: Gothic horror became my church, and Boris Karloff my Messiah,”
Guillermo del Toro, director
Release Dates and Anticipation for Frankenstein’s Debut
Frankenstein will have a limited theatrical release starting October 17, 2025, before becoming available globally on Netflix beginning November 7. With that window approaching, the recent Oscar Isaac Frankenstein clip and promotional materials offer an intriguing preview of del Toro’s dark, intense interpretation of this classic tale, promising viewers a film that is both emotionally complex and visually striking.
https://twitter.com/_filmcrave/status/1980657833340506348
Good Morning! Here is the full, uncropped poster I did for @RealGDT @FrankensteinGDT pic.twitter.com/vohBJma0zX
— James Jean (@JamesJeanArt) October 20, 2025
Oscar Isaac. Victor Frankenstein.
FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7. pic.twitter.com/dKBljDvWqY
— Netflix (@netflix) October 13, 2025
Jacob Elordi. The Creature.
FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7. pic.twitter.com/MksoOLMXEw
— Netflix (@netflix) October 13, 2025
Mia Goth. Elizabeth Harlander.
FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7. pic.twitter.com/hYCZFnVCSP
— Netflix (@netflix) October 13, 2025
Felix Kammerer. William Frankenstein.
FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7. pic.twitter.com/P4d1n574dL
— Netflix (@netflix) October 13, 2025
Christoph Waltz. Heinrich Harlander.
FRANKENSTEIN, a film by Guillermo del Toro. Coming to select theaters October 17 and on Netflix November 7. pic.twitter.com/rUESRymgE8
— Netflix (@netflix) October 13, 2025
